Virion (NGO). NPO Microgen specialists received awards from the Ministry of Health of the Russian Federation

Combined drug.

Glucosamine

Stimulates the production of cartilage matrix, promotes regeneration processes, has a moderate anti-inflammatory effect.

Chondroitin sulfate

It is the main component of proteoglycans, which, together with collagen fibers, make up the cartilage matrix. It acts as a chondroprotector, inhibits the activity of enzymes that contribute to the degradation of the cartilage surface of the joint, activates the metabolism in the subchondral bone, stimulates the production of proteoglycans by chondrocytes and the regeneration of cartilage tissue. It has an analgesic and anti-inflammatory effect, inhibits the secretion of prostaglandin E 2 and leukotriene B 4, reduces the excretion of inflammatory mediators into the synovial fluid.

Prevents the collapse of the connective tissue, promotes the restoration of articular surfaces, improves the production of intra-articular fluid, resulting in improved mobility in the joint and reduced pain intensity.

Glucosamine

After oral administration, it is absorbed in the gastrointestinal tract. It undergoes primary metabolism in the liver. Bioavailability is 25%. Up to 30% of the amount of the drug taken accumulates in bone and muscle tissue.

Chondroitin sulfate

After ingestion on an empty stomach, up to 13% is absorbed in the gastrointestinal tract. The maximum plasma concentration is reached after 3-4 hours. After 4-5 hours accumulates in the synovial fluid.

The half-life is 68 hours. Elimination with faeces.

It is used to treat degenerative-dystrophic diseases of the joints and spine in osteochondrosis and osteoarthritis I - III degree.

Age up to 15 years, severe renal failure, phenylketonuria, pregnancy and lactation, individual intolerance.

Bronchial asthma, diabetes mellitus, hemophilia.

Inside, 1 capsule 3-4 times a day for 3 weeks, then 1 capsule 2 times a day for up to 3-6 months.

The highest daily dose: 4 capsules.

The highest single dose: 1 capsule.

Glucosamine

Central and peripheral nervous system : headache, dizziness, insomnia, drowsiness.

The cardiovascular system : tachycardia, peripheral edema.

Digestive system : flatulence, epigastric pain, constipation or diarrhea.

Allergic reactions.

Chondroitin sulfate

Allergic reactions.

Cases of overdose are not described.

Treatment is symptomatic.

Increases the absorption of tetracyclines.

Reduces the effects of semi-synthetic penicillins.

Despite the fact that in recent years many people are increasingly thinking about their own health, some ailments cannot be avoided. In particular, a fairly common problem is joint damage, which progresses with age. No one succeeds in avoiding the development of degenerative-dystrophic processes, but in order to slow down the rate of their progression, special prophylactic agents can be used, for example, glucosamine chondroitin complex.

Description

The most popular form of application are tablets or capsules. A fairly well-known product of the Solgar company, a well-known manufacturer of dietary supplements (biologically active additives), is the Glucosamine Chondroitin Complex, which is produced in a package of 90 pcs.

The composition of dietary supplements

Let us dwell separately on each component that is part of the Glucosamine Chondroitin complex.

Glucosamine is present in the body of any person and ensures the normal functioning of the musculoskeletal system. With age, its concentration decreases, which causes changes in the joints. Externally obtained glucosamine will stimulate the formation of natural proteoglycans and hyaluronic acid. In addition, glucosamine sulfate has protective properties. It prevents damage to cartilage by free radicals and enzymes that destroy cartilage. Glucosamine is especially useful for people taking NSAIDs (non-steroidal anti-inflammatory drugs), because they are known to damage cartilage by breaking down glycosaminoglycans. Glucosamine prevents this process, thereby positively affecting the joints.

Chondroitin is also a structural element of cartilage. In the body, it is responsible for the viscosity of the intra-articular fluid, restoring its normal values. Chondroitin also protects cartilage from enzymatic effects, thereby preventing the destruction of cartilage tissue.

Methylsulfonylmethane is a source of sulfur. This is a sulfur-containing substance with a pronounced anti-inflammatory effect. It is found in many dietary supplements, but in combination with chondroitin and glucosamine gives the maximum effect. In addition to its anti-inflammatory effect, methylsulfonylmethane improves the permeability of cell membranes, helping to improve the supply of nutrients to the joints.

All three components will contribute to:

1. Acceleration of regeneration processes.
2. Reducing pain and inflammation.
3. Improving the function of the joints.
4. Slow down the gradual destruction of cartilage tissue.
5. Protection of cartilage from the damaging effects of concomitant drug therapy (NSAIDs, hormones, etc.)

All the properties that the tablets have will help to improve the joints and improve the quality of life of a person with degenerative-dystrophic lesions of the musculoskeletal system. All of the above confirms the instructions for use and the positive reviews of doctors about the chondroprotector.

When appointed

As the instructions for use say, the glucosamine-chondroitin complex can be prescribed for:

• Arthrosis.
• Arthritis.
• Osteochondrosis.
• Arthropathy.
• Spondylosis.
• Other degenerative-dystrophic diseases of the musculoskeletal system.

In some situations, capsules or tablets with a chondroprotective effect may be prescribed for prophylactic purposes. They can be recommended to athletes whose joints wear out much faster, the elderly, patients with diagnosed arthrosis that does not manifest itself clinically.

Method of administration

The instructions for use indicate the following method of administration:

• First 3 weeks: 1 caps. 2 r / day.
• Subsequently, they switch to 1 caps. 1 r / day.

The duration of the course of treatment will be determined by the doctor on an individual basis. Some tablets, capsules and dietary supplements in other pharmacological forms of release, patients can take up to six months. In some cases, such instructions are given by the instructions for use. However, any extension of the course must be agreed with a specialist.

Other forms of release

The described forms of release of dietary supplements from Solgar are not the only ones. We found several other brands that produce drugs called glucosamine chondroitin complex:

• Complex glucosamine chondroitin, gel. From the name it is clear that the medicine is intended for external use. The gel has the following composition:

1. Glucosamine.
2. Chondroitin.
3. Sabelnik (extract). The plant extract of cinquefoil is not in vain included in the gel. The beneficial effect of the plant was noted by our ancestors. The composition of the plant extract includes vitamins (in particular, vit. C), saponins, resins, trace elements, flavonoids. Sabelnik, and hence the gel, has anti-inflammatory, regenerative, tonic, analgesic, wound healing effects, which is confirmed by the reviews of phytotherapists.
4. D-panthenol. It has regenerative and restorative properties.
5. Essential oils of juniper and sage.

Given the above, we conclude that the gel actually has a beneficial effect on the joints. You should not count on a systemic effect from the external use of the glucosamino-chondroitin complex, but the local effect on nearby tissues will be good.

• Glucosamine chondroitin complex ultra (GCC ultra), caps. 90 pcs.

Composition of one capsule

Capsules with the Ultra prefix are used in 1 caps. 3 r / day, unless another scheme is prescribed by the attending physician.

• Complex glucosamine chondroitin, 90 pcs. According to the instructions for the drug found by us, the complex has the following composition:

Having taken 3 tablets of the complex per day, a person receives the daily norm of the necessary substances, so the manufacturer has indicated just such a frequency of use: 1 pc. 3 r / day. The duration of the course should be determined by the doctor.

Mention of contraindications and side effects

If we talk about contraindications to any form of release of the glucosamine-chondroitin complex, then they will be similar for all drugs. Contraindications are:

• Pregnancy and lactation.
• Thrombophlebitis and violation of normal blood clotting.
• Diabetes.
• Severe diseases of the kidneys and liver, accompanied by organ failure.
• Individual intolerance to the drug.

We did not find clear instructions regarding the appointment of the complex for children. The general recommendation for the use of chondroprotectors in children is a ban on the use of drugs without a thorough analysis of the indications for its use. Medicines containing chondroitin and glucosamine can be prescribed to babies, but only after examination and under the supervision of the attending doctor.

Reading the reviews of people and specialists, we can conclude that the remedy is generally well tolerated. In rare cases, during the application were observed:

1. From the side of the stomach and intestines: dyspepsia (stool disorder, nausea, vomiting, bloating).
2. From the nervous system: headaches, dizziness, drowsiness.
3. With local application of the gel, allergic reactions on the skin may develop: the appearance of redness, irritation, itching.

There is no specific antidote, that is, a substance that neutralizes the effect of the drug. With the development of side effects, it is recommended to stop therapy and consult a doctor for advice.

Price

On the Internet and a stationary pharmacy network, the price for various forms of release of the complex is different. We have compiled averages for your convenience.

Price for popular products

About some drugs you can read both negative and positive reviews. Note that many doctors are not as categorical in their opinion as people who did not feel the effect of a single application of the complex. Experts believe that the lack of a pronounced satisfactory effect may be due to the advanced stage of the process, the presence of pronounced changes in the joints, as well as the individual characteristics of a person.

Therefore, with the relatively low effectiveness of the first course of chondroprotectors, for example, the glucosamine-chondroitin complex, one should not despair. In some cases, even the absence of negative changes will serve as a good indicator. In such situations, it is important to listen to the opinion of doctors, then the productivity of treatment increases significantly.

Glucosamine Chondroitin Complex Ultra
Buy Glucosamine Chondroitin Complex Ultra in pharmacies

MANUFACTURERS
Pharmacore production (Russia)

GROUP
Food supplements that support the functions of the musculoskeletal system

INTERNATIONAL NON-PROPRIETARY NAME
No

Composition:

Glucosamine sulfate
chondroitin sulfate
methylsulfonylmethane (MSM)
boswellia extract

Action:

Methylsulfonylmethane (MSM) is a tasteless and odorless organic sulfur-containing compound, which is a source of naturally occurring sulfur in a biologically available form. MSM is the best source of active organic and significantly outperforms all other sulfur compounds in its positive properties. In the body, sulfur is necessary for the formation of muscles, ligaments, cartilage, connective tissue, nails, hair and skin. Sulfur is a necessary element for the synthesis of proteins involved in the construction of joints and ligaments. As people age, the concentration of sulfur in the body decreases, especially as a result of diets and metabolic disorders. Since sulfur plays an important role in human life, it must be present in the diet. MSM as a source of sulfur in a biologically available form is used for joint problems, as well as for poor skin, hair and nails.

Glucosamine participates in the biosynthesis of hyaluronic acid and proteoglycans necessary for the formation of articular cartilage and collagen synthesis, contributes to the normal deposition of calcium in bone tissue.

Chondroitin is a high molecular weight polysaccharide, which is found in significant amounts in connective tissue, especially in cartilage. Due to the viscosity and characteristics of the chemical structure, chondroitin prevents the contraction of the connective tissue and plays the role of a kind of lubrication of the articular surfaces.

Boswellia extract contains boswellic acids, which have a significant anti-inflammatory effect, help reduce pain, improve joint and spine mobility.

adults 1 capsule 3 times a day with meals. Duration of admission - 1 month. If necessary, the reception can be repeated.

Contraindications:

individual intolerance to the components of the product, pregnancy and lactation. Before use, you should consult with your doctor.

Release form:

60 or 90 capsules in a polymer jar.

Storage conditions:

store in a dry place, protected from light, out of the reach of children, at a temperature not exceeding +25°C.

Best before date:

2 years. Is not a medicine.
For whom is the complex "GHK-Ultra" in capsules recommended?

For adults over 18 who:

predominantly lead a sedentary and sedentary lifestyle
have problems with the musculoskeletal system
experiencing physical stress on ligaments and joints
doing various sports