Home Potato Can vardenafil be mixed with sildenafil? When and to whom is sildenafil citrate prescribed, how to take it correctly. Are there any contraindications

Can vardenafil be mixed with sildenafil? When and to whom is sildenafil citrate prescribed, how to take it correctly. Are there any contraindications

Super P-Force Sildenafil and Dapoxetine Tablet- this drug has embodied the dreams of many millions of men. Most men (and their partners too!) want the sexual intercourse to last much longer than the average 3-5 minutes, and that the erection be powerful all this time. Try this tool at least once, be sure you will like it!

SUPER P-FORCE is a drug that helps the male sex cope with problems that arise in the intimate area. Its main advantage is that it contains Dapoxetine and Sildenafil, which actively influence the normalization of blood circulation in the penis.

Indications for use:

  • disorders that are associated with premature ejaculation;
  • weakness of potency.

Thanks to the main active ingredients, the product normalizes blood circulation and restores erectile function in a couple of hours. In addition, intimacy lasts much longer due to the delay in ejaculation. The half-life of the drug is from 5-6 hours, and the effectiveness occurs 40-90 minutes after the first dose.

Composition: Each tablet contains 2 main substances: Sildenafil (100 mg) and Dapoxetine (60 mg).

Super P-Force instructions for use: the initial dosage ranges from 25-100 mg per day. The drug should be taken 1-3 hours before intimacy.

Caveats: Super P-Force is not recommended for combination with antidepressants, cytocytic inhibitors, monoamine oxidase inhibitors, imidazoles and nitrates.

Side effect: in the course of treatment with this drug, no obvious side effects that entail serious health problems were found. However, in rare cases, minor changes in the condition may occur: headache, dizziness, diarrhea, nausea. Strengthening side effects is possible only with an increase in the recommended dose, so you should first consult with a specialist.

Contraindications:

  • sensitivity to the active ingredients of the drug;
  • arrhythmia;
  • cardiovascular diseases;
  • aortic stenosis;
  • heart failure;
  • lactose intolerance;
  • hypotension;
  • hypertension;
  • mental and nervous disorders;
  • cirrhosis of the liver;
  • convulsive syndrome and epilepsy;
  • dizziness of unknown origin;
  • hypertrophic obstructive cardiomyopathy;
  • previous myocardial infarction and stroke;
  • the drug is not recommended for women and children, as well as men under 18 years of age.

Less severe contraindications include:

  • exacerbation of a gastric ulcer or duodenal ulcer;
  • thrombocytopenia;
  • tendency to form bleeding;
  • multiple myeloma;
  • sickle cell anemia;
  • leukemia;
  • deformation of the penis.

Package: 4 tablets in a blister, each containing 100 mg Sildenafil Citrate Sildenafil Citrate and 60 mg Dapoxetine Dapoxetine. Blister weight approx. 4 g. Weight with packaging 7 g.

Keep in a dry cool dark place away from children.

Best before date: 3 years.

Production: RSM Ltd., India.

Leave about Super P Force

Sildenafil - what is it and how does it work? Before answering the question posed, let's deal with the natural process of erection. The physiological mechanism of male arousal and the appearance of an erection involves the release of nitric monoxide from the cavernous bodies, which is an activator of the guanylate cyclase enzyme. These two compounds react to form a new enzyme, cyclic guanosine monophosphate. As a result of this reaction, the smooth muscles of the penis relax, and the blood flow in the penis increases several times. Cavernous bodies absorb blood to the maximum, hardening and increasing in size.

The described mechanism of erection stops when cGMP-specific enzyme type 5 phosphodiesterase appears in the blood. It breaks down guanosine monophosphate, which leads to smooth muscle tension and a decrease in the cavernous bodies. Usually this process begins after reaching orgasm. But if the functioning of the reproductive system is impaired, PDE-5 is constantly present in the blood, preventing the appearance of an erection. Sildenafil drugs block the action of phosphodiesterase, helping to start the erection mechanism. It should be noted that the drug helps to restore the natural process of sexual arousal. Therefore, without sexual stimulation, there will be no erection.

Effect on women

Everyone knows that the female genital organs are excited according to a similar principle with the male ones. Therefore, attempts to use Sildenafil citrate to increase female libido are constantly being made. Many note a noticeable or slight increase in sexual desire, sexual desire, pleasant sensations during orgasm. The official instructions indicate that Sildenafil citrate is not used to treat women. Apparently, this only means that the effect of the active substance on the female body has not been specifically studied. To accurately understand whether the drug helps the fair sex, more research is needed.

Additional materials:

Validity

The drug Sildenafil citrate begins to act after 15-25 minutes. The maximum concentration of Sildenafil in the blood is observed after 1.5-2.5 hours. The period of action is 4 hours. During this time, you can engage in sexual activity even in the presence of serious disorders in the functioning of the reproductive system. There is evidence that in some men Sildenafil (Sildenafil citrate) acts up to 6 hours. This indicator is quite strongly influenced by the fat content and density of food. High-calorie, high-fat foods (pizza, hamburgers, etc.) can not only delay the onset of the effect, but also adversely affect the effectiveness of the drug.

Male potency is an important component of the health of every male body. It is the erectile function that most men put in the foreground in their lives and are very panicked if suddenly something did not work out in bed with a partner. Fortunately, modern methods and methods of treatment allow, at the first manifestations of the disease, to cure it, and right now we will talk about one drug that quickly restores male sexual dysfunction.

Sildenafil citrate, or in other words the same Viagra, is a drug that was registered at the end of the 20th century and was intended for the treatment of erectile dysfunction in the male body.

Already a few years after the registration of the named remedy, more than ten million men around the world have tried this drug on themselves and 80% of them were satisfied with Sildenafil. At the same time, studies of the drug continued, and the instructions for its use began to be supplemented with new useful instructions.

Conducting additional research, scientists realized that the drug can have its therapeutic effect on the treatment of potency without side effects even on diabetics and people who have a malfunction in the cardiovascular system and spinal cord injury.

The results of a study on the use of Sildenafil citrate in patients with prostate cancer, depressed people and patients with Parkinson's disease were also encouraging. All of them showed improvements in erectile function, and no side effects were observed.

Most of the side effects that were found by specialists in the initial studies of the drug were mild or moderately severe. There were extremely rare cases when the treatment with the named remedy had to be stopped. These cases are less than 1% of all.

Pharmacological properties of Sildenafil, release form

Sildenafil citrate is available in coated tablets. The package contains one or more blisters of one tablet or four tablets on one such blister. Each package contains instructions for using the remedy that has a therapeutic effect.

Before starting treatment with Sildenafil tablets, the instructions for its use must be read. It is necessary to purchase tablets after consulting a doctor. Self-medication can lead to disastrous consequences.

Sidenafil citrate 140 mg tablets contain 100 mg of seldinafil itself.

  • cellulose microcrystalline;
  • lactose monohydrate;
  • magnesium;
  • povidone;
  • indigo carmine;
  • titanium dioxide.

If initially the drug was developed as a remedy for the treatment of cardiovascular diseases, today the main purpose of Sildenafil, as the instructions say, is to increase erectile function in men.

The medicine helps to restore lost sexual arousal. When taking the named drug, depending on the characteristics of the organism and the causes of the onset of the disease, the erection is restored to 100%.

Under the influence of Sildenafil, cyclic guanosine monophosphate (cGMP) breaks down, blood circulation and blood filling of the muscles of the male penis increases. In 77% of men after taking the drug, erectile dysfunction is completely restored and a representative of a strong half is able to perform a normal, full-fledged sexual intercourse.

The drug is taken 40-50 minutes before intimacy, the effect of Sildenafil lasts up to 4 hours.

Side effects and contraindications

Despite the effectiveness of the drug and the minimal side effects from taking it, such effects are still observed in some cases.

  • the appearance of a headache;
  • severe reddening of the face due to a rush of blood to it;
  • visual impairment;
  • the appearance of dyspepsia;
  • congestion in the sinuses;
  • skin rash;
  • infections in the urinary system;
  • dizziness;
  • diarrhea.

In a number of cases (isolated cases) there were observed: fainting, ringing in the ears, dry mouth, tachycardia, photophobia, swelling of the genital organs, arthritis, frequent urination, thirst for water, increased sputum when coughing, and some others. Such effects were recorded when taking the drug at a dosage of 100 mg. No such side effects were observed at lower dosages.

It may be that Sildenafil is contraindicated for some individuals at all.

Medical contraindications include:

  • hypersensitivity to the components of the drug;
  • deformation of the penis;
  • parallel treatment with nitrate preparations;
  • kidney failure;
  • frequent bleeding;
  • cirrhosis of the liver;
  • severe hypertension;
  • heart disease (strokes and heart attacks);
  • unstable angina;
  • arrhythmia.

How to use Sildenafil and dosage

As the instructions say, Sildenafil tablets should be taken 50-60 minutes before sex.

A single dose per day for adult men is not more than 50 mg.

The dosage of the drug is prescribed only by a doctor. Do not self-medicate, remember, this can lead to disastrous consequences.

Given the patient's tolerance to the components of the drug and the individual characteristics of his body, the doctor may lower the single dosage to 25 mg or, on the contrary, increase it to 100 mg. Only the doctor decides!

100 mg is the maximum allowable daily dosage of the drug.

For men aged 45 and older, it is not recommended to change the daily dose of 50 mg in either direction. This can lead to undesirable consequences if the dosage is increased or will not bring the desired effect if the dosage is reduced.

How to use Sildenafil in patients with renal insufficiency and is it possible to use the drug while taking other drugs?

  1. In the presence of cirrhosis of the liver or renal failure of any severity, the drug can be prescribed, however, a single dose of the drug is reduced in dosage to 25 mg.
  2. It is strictly forbidden to take Sildenafril in parallel with nitrates. In addition, it is recommended to reduce the dosage of the drug to 25 mg if the patient is taking CYP3A4 inhibitors (with the exception of Ritonavir, with which Sildenafril is contraindicated) and alpha-adrenergic receptor blockers.

It is forbidden to use Sildenafril citrate for persons under 18 years of age, as well as for patients over 75 years of age.

With an overdose of Sildenafil, patients experience pronounced side effects - dizziness, rash, blurred vision, blood in the urine, and others. As a rule, such effects are observed when taking more than 100 mg of the drug per day.

The higher the dosage, the greater the severity of side effects observed and it is important to remember and know this. For the treatment of overdose symptoms for men, the doctor prescribes special symptomatic therapy.

Precautions while taking Sildenafil

Before you start taking Sildenafil, it is important to consult a doctor.

The specialist, prescribing the drug, examines the patient's tests, identifies the causes that affected the sexual function of the male body, and only then prescribes the treatment.

Before prescribing a medicine, a man must undergo a general clinical and urological examination.

The drug may be contraindicated for those who, for a number of clinical (physiological) reasons, have unwanted sexual activity. These can be people with various forms of heart disease, as well as patients with kidney failure, cirrhosis of the liver, men over 70, etc.

When prescribing, the doctor takes into account not only physiological contraindications, but also contraindications for taking Sildenafil with other drugs. So, as already noted, the use of the named drug with nitrates is not recommended.

Sildenafil is not indicated for use in women, as well as in children and adolescents under the age of 18 years.

Special instructions for the use of Sildenafil

Before taking Sildenafil, as a drug that normalizes erectile dysfunction, it is important for the patient to undergo a heart examination, as well as to conduct an examination of the vascular system.

With extreme caution, Sildenafil is prescribed to men who have anatomical deformities of the penis (for example, cavernous fibrosis, etc.), as well as to people predisposed to leukemia, sickle cell anemia and multiple myeloma.

Sildenafil should not be taken by men who, for one reason or another, are contraindicated in sexual activity.

With extreme caution should be approached when taking the drug to people:

  • prone to frequent bleeding;
  • with duodenal disease in the process of exacerbation of the disease;
  • with peptic ulcer;
  • with retinitis pigmentosa.

You can not take Sildenafil citrate, even in the smallest dose, to persons under 18 years of age.

As for driving while taking the medicine, doctors note that there is no effect of the drug on drivers, and therefore Sildenafil tablets can be used by those who are going to drive.

Sildenafil's analogs

An analogue of Sildenafil citrate is any drug of the same pharmacological group, that is, a medicine that has Sildenafil in its composition and has the same medicinal property.

In the modern market of medicines, there are a huge number of analogues of Sildenafil. The most popular among them are: Viagra, Dynamico, Pemegra, Tornetis, Silafil, Viprogra, Edegra, Kamagra, etc.

The first, most famous and most effective analogue of Sildenafil is Viagra. Today, this drug to increase erectile male function can be bought at any pharmacy.

What is the main difference between analogues and originals?

  1. Analogues are cheaper.
  2. When developing the original, special studies, experiments are carried out, side and other effects are revealed, and only then a technique is developed for cleaning the main element from impurities, the best technique for taking the drug and its dosage. Such a drug is patented and put on the market. In the case of analogues, pharmacological companies simply use the main substance of the original drugs, supplementing them with others. The result is a new medicine with a new name (name) and already at a different price than the original.

Sildenafil Citrate for Women

Sildenafil, as doctors point out, is a purely male drug that serves to maintain and restore potency in men. Meanwhile, the properties of the main substance of the drug are able to lower the pressure in the pulmonary artery, and therefore the drug can be prescribed to people suffering from a mild form of pulmonary hypertension. It can be women, but in such cases the drug will have a slightly different name.

Sildenafil for women is available under the brand namesfemalegra,Ladygra and Womenra.

The active substance in these preparations is the same Sildenafil citrate.

When taking the medicine, women also experience some side effects.

These include:

  • violation of visual function;
  • nasal congestion;
  • dizziness and headache;
  • fear of the world.

Sildenafril citrate for the fair half not only relieves hypertension, but, as experts point out, it has the same effect as on men - the effect of restoring sexual desire.

Before taking the drug, it is important to consult a doctor.

Conclusion

Clinical studies for more than 3 years and about 10 more years of close observation of the effectiveness of the drug in humans have practically not changed the first ideas about the safety and effectiveness of Sildenafil.

Sildenafil is well tolerated by almost all groups of men, including those who have a psychogenic, organic and mixed etiology of erectile dysfunction.

Today, the drug is used all over the world, has hundreds of analogues. Tolerability of the components of the drug is good, the number of people who experienced serious side effects from taking Sildenafil is minimal (less than 1% of all patients who have tried the drug).

Drawing conclusions

Did you have a misfire? Judging by the fact that you are reading this article, victory is not on your side.

And of course, you know firsthand that a violation of potency is:

  • Low self-esteem
  • Women remember your every failure, tell their girlfriends and your friends
  • prostate disease
  • Developing depression that negatively affects your health

Now answer the question: DOES THIS SUIT YOU? Can this be tolerated? Do you remember that feeling when you look at a naked woman and can't do anything? Enough - it's time to get rid of problems with potency, once and for all! Do you agree?

We have studied a huge amount of materials and, most importantly, tested most of the means for potency in practice. So, it turned out that a 100% working drug without any side effects is Predstanol. This drug consists of natural ingredients that completely exclude chemistry.

ATTENTION! STOCK! You can try the drug is free order by clicking the link or by filling out the form below.

Erectile dysfunction is a problem that many men suffer from. Problems with intimate life can occur both in the presence of serious illnesses, and as a result of severe stress or mental trauma. In any case, representatives of the stronger sex are extremely sensitive to this topic.

Fortunately, problems with lack of erection can be solved. Quite often, patients are prescribed the drug Sildenafil Citrate, also commonly known as Viagra. And many people are interested in questions about what this remedy is and how exactly it affects the body. How much does the drug cost? Are there any complications associated with taking it?

The composition and form of release of the drug

The drug "Sildenafil" is available in the form of small oval blue or blue tablets. On the fault they are white and almost white. In a pharmacy, you can buy blister packs with 1, 2, 4, 10 or 20 tablets.

The main active substance is sildenafil citrate - 100 mg, 50 mg or 25 mg in each tablet. Naturally, other excipients are present in the composition, in particular lactose monohydrate, magnesium stearate, croscarmellose sodium, and povidone. The film shell consists of macrogol, talc, titanium dioxide, as well as dyes based on iron and aluminum.

Main pharmacological properties

Sildenafil citrate is nothing more than a selective inhibitor of cycloguanosine monophosphate, a specific type 5 phosphodiesterase, which is responsible for the breakdown of cGMP.

In order to understand the mechanism of action, it is worth first considering the process of erection. It is associated with the release of nitric oxide in the cavernous body, which leads to an increase in cGMP levels, relaxation of the smooth muscles of the corpora cavernosa and an increase in blood flow - this ensures an erection of the penis.

Sildenafil does not directly affect the corpus cavernosum. But, due to the inhibition of phosphodiesterase, an increase in the level of cGMP is observed, which enhances the effect of the released nitric oxide and, accordingly, ensures that the cavernous body is filled with a large volume of blood.

After ingestion, the active substance is absorbed almost instantly. On average, its bioavailability is 40-60%. As a rule, the effect of taking the drug appears 60 minutes after ingestion, although this figure can vary from 30 to 90 minutes. Metabolism of the active substance occurs in the liver. The products of metabolism are excreted by the intestines and kidneys. That is why taking pills by patients suffering from disorders in the functioning of the kidneys and liver is possible only after a thorough examination by a doctor.

What are the indications for use?

Perhaps the only indication for the use of the drug "Sildenafil citrate" is namely the inability to achieve and maintain an erection. It should be noted that this drug is effective only in the presence of appropriate sexual stimulation. And the Sildenafil Citrate tablets are not intended for women. After all, this drug is not a causative agent, its mechanism of action is associated with an increase in blood flow, which provides an erection, but not with an increase in sexual desire.

The drug "Sildenafil citrate": instructions and doses

Immediately it is worth noting that before you start taking the pills, you need to consult a doctor. Only a specialist can accurately select the most effective dose. As a rule, men are first prescribed to take 50 mg of the active ingredient. In the absence of the necessary reaction, the amount is increased to 100 mg. If, on the contrary, the initial dose caused side effects, it is reduced to 25 mg. At a time, you can take no more than 100 mg of the active substance. It is not recommended to use the tablets more than once a day. The dosage for people suffering from kidney and liver disease is 25 mg.

Are there contraindications?

Immediately it should be said that this medicine has contraindications, the list of which must be read:

  • hypersensitivity to any of the constituent substances (carefully read the composition before use);
  • since Sildenafil Citrate enhances the action of nitrates, it cannot be used along with other nitric oxide donators, any form of nitrates and nitrites;
  • disorders of lactose metabolism, in particular its intolerance, as well as lactase deficiency, glucose-galactose malabsorption;
  • the drug is not intended for patients under the age of 18, as well as for women.

There are also so-called relative contraindications, against which the reception is possible, but only with all possible caution. This group includes various anatomical deformities of the penis, leukemia, thrombocythemia, hereditary diseases accompanied by bleeding, including periods of exacerbation of peptic ulcer of the stomach and intestines.

Potentially dangerous are such ailments as hypertension, hypotension, unstable angina, heart failure, stroke, recent myocardial infarction.

What are the possible side effects?

Although the drug rarely causes serious side effects, they are still possible. These include:

  • pain in the abdomen and chest, chills, swelling of the face, asthenia, increased sensitivity to light;
  • allergic reactions;
  • disorders of the nervous system, including increased drowsiness or insomnia, parasthesia, neuralgia, unusual dreams, convulsions, stroke, ataxia, decreased reflexes;
  • problems in the work of the cardiovascular system, including an increase or a sharp decrease in blood pressure, myocardial infarction, tachycardia, fainting, arrhythmias, cerebral thrombosis, cardiomyopathy and heart failure;
  • shortness of breath, cough, nosebleeds, sinusitis, bronchitis, increased cough, asthma attacks and some other disorders of the respiratory system;
  • disorders of the digestive tract, namely nausea, vomiting, glossitis, colitis, stomatitis, gingivitis, rectal bleeding, dryness of the oral mucosa, dysphagia;
  • on the part of the sense organs, pain in the eyes, visual disturbances, cataracts, conjunctival damage, pain and noise in the ears, vertigo, deafness are possible.

Other side effects include synovitis, atrites, myalgia, bone pain, peripheral edema, pathological thirst, development of gout and unstable diabetes, as well as skin ulcers, anorgasmia, increased sweating, urinary incontinence, persistent and too long erection.

Is an overdose possible?

There is no exact information about drug overdose. However, the constant use of too high doses of Sildenafil Citrate increases the likelihood of side effects, namely dizziness, heart palpitations, color vision disorders, diarrhea, and nausea. That is why it is necessary to strictly observe the doses recommended by the doctor, and if there is any deterioration, immediately consult a specialist.

The drug "Sildenafil citrate": price

Of course, for many patients, the question of the cost of a particular drug is extremely important. So how much will the medicine "Sildenafil citrate" cost? The price in this case fluctuates widely. Everything here depends on the manufacturer, the trade name (there are several drugs with the same basic composition), the pricing policy of the pharmacy, the city of residence, etc.

70-110 rubles - this is how much one tablet of the drug "Sildenafil citrate" will cost. You can also buy a whole package at a pharmacy, but its cost, of course, will be higher - about 1,100 rubles.

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