Anyone knows that the habit of smoking is harmful and causes colossal harm to health.
Starting to smoke around adolescence for the sake of the image and the desire to seem adults, the young man does not even suspect into what trap he is pulling himself with his own hands.
Any smoker naively believes that he can quit a cigarette at any time of his own free will. The day comes when he thinks about his health and decides to quit smoking. But it was not there! In fact, it turns out that this is not so easy. Some people spend a lot of time to say goodbye to nicotine addiction.
Nicotine Deficiency Symptoms
Constantly receiving nicotine from a cigarette, the body stops producing its own natural nicotine. After smoking a cigarette, it disappears from the blood in about a few hours, and the smoker feels physical withdrawal - a lack of nicotine. It manifests itself as follows:
- Depressed mood.
- Irritability and nervousness.
- Insomnia.
- Intense desire to smoke.
- Falling blood pressure.
- Disorder of memory and thought processes.
Avid smokers claim that they are ready to commit a crime for the sake of a cigarette at the moment when there is no cigarette and the desire to smoke is very strong.
The very process of smoking is a ritual: lighting, bringing a cigarette to the mouth, blowing a stream of smoke, talking while smoking, coffee with a cigarette. Such a ritual becomes an integral part of a smoker's life: ate - smoked, did a difficult job - "smoked" him, a stressful situation - a cigarette relieves stress and tension. And not everyone can lose this part painlessly, because they will have to reconsider many things related to the cigarette ritual. This is about psychological addiction.
Types of addiction
Thus, the habit of smoking is caused not by one, but by two dependencies: physiological and psychological.
What is nicotine? It is the strongest poison, a herbal drug. It looks like a clear liquid, similar to oil, very bitter in taste. For humans, a lethal dose is 2-3 drops of pure nicotine. But in minimal quantities, it is able to help smokers get rid of the smoking habit. The manufacturers of nicotine patches are based on this principle.
How the patch works
At present, bad habits and generally an unhealthy lifestyle are fading into the background, giving way to healthy lifestyle and sports. Therefore, more and more people strive to get rid of cigarettes and be in trend. Some are pushed to a cigarette-free life by health problems that began precisely because of smoking.
There are many ways that you can help ease the pangs of withdrawal. One of them is anti-smoking patches, which is a layer of nicotine on a medical patch. The patch comes in round, square, oval, and different sizes.
Their principle of action is the same for different manufacturers: after gluing to the skin, a therapeutic nicotine enters the bloodstream and reaches a maximum after 6 hours of wearing... A distinctive feature of this method is the absence of a harmful effect on the body. Getting nicotine in this way, the smoker gets out of the habit of cigarettes, without suffering from physical withdrawal.
By gradually reducing the dosage of nicotine in the patch, over time, the smoker gives up the addiction forever. The average time to get rid of tobacco addiction is approximately 2 months.
Some manufacturers make patches with analog nicotine substitutes, containing various substances that have a beneficial effect on the body. It is recommended to place the patch on the thigh or arm - these are the most successful places, they have a large number of small vessels through which nicotine will penetrate into the blood.
What happens in weeks if you quit smoking:
- Your efficiency will increase, energy and strength will return.
- The volume of the lungs will increase several times and will be able to process 80% more oxygen.
- The body will completely get rid of tar, waste and toxins.
Advantages and disadvantages of the method
The main advantages of the anti-nicotine patch are as follows:
Despite the many advantages of this anti-smoking method, nicotine patches also have disadvantages. There are not many of them, but they are still there.
- There is a risk that the addiction will resume after discontinuation of use.
- The effectiveness of the patch may decrease with prolonged use.
Side effects:
- Allergic skin reactions such as itching and rashes are possible.
- An incorrectly calculated dose of nicotine can lead to overexcitation and insomnia.
Selection rules and drug review
Today in pharmacies you can find adhesive plasters from different manufacturers. We present to your attention the most popular of them.
Holders of the patent RU 2572720:
The invention relates to the pharmaceutical industry and is an anti-nicotine agent containing in 1 dose 50-200 mg of theanine and 8-50 mg of tryptophan, and may additionally contain nicotine in an amount of 1-1.5 mg or an alkaloid with a nicotine-like effect selected from the group : lobelia hydrochloride 1-1.5 mg, anabazine hydrochloride 1-2 mg, cytisine 0.5-1 mg. EFFECT: reduction of the number of smoked cigarettes per day, improvement of mood, absence of nervousness. 2 c.p. f-ly, 4 pr.
The invention relates to pharmaceuticals and parapharmaceuticals, and in particular to means for smoking cessation.
Currently, in connection with the fight against smoking at the state level, the problem of helping people trying to quit smoking has become more urgent. Sufficiently effective means for this have not yet been developed all over the world.
The difficulty in withdrawing from cigarettes lies in the nature of the mechanism of dependence on smoking, which affects all systems of the human body. Physical nicotine addiction is caused by the participation of nicotine in the biochemical processes of the body. Psychological based on the fact that smoking tones up and improves mood.
Nicotine is known to increase levels of dopamine (a neurotransmitter that induces feelings of pleasure) and endorphin, the "happiness hormone". A decrease in the intake of nicotine in the body is accompanied by severe psychological discomfort, depression, anxiety, and decreased performance. Both components of nicotine addiction are interconnected. But at the same time, psychological dependence remains dominant and more prolonged.
Existing methods of smoking cessation assistance are aimed mainly at specific links of nicotine addiction (nicotine replacement, nicotinic receptor antagonist therapy, antidepressant therapy, restorative and sedatives).
There are widely known anti-nicotine drugs based on nicotine and alkaloids with nicotine-like action Tabex, Lobesil, Gamibazin, Nicoretto, Nicotinell, etc., produced in various forms (tablets, chewing gums, cigarettes, transdermal systems, etc.). These agents facilitate smoking cessation, but are substitution therapy, reduce the physical symptoms of withdrawal and have no effect on the psychological component of nicotine addiction.
Antagonists of nicotinic acetylcholine receptors Varenicline (Champex) and the antidepressant Bupropion are more effective.
There are also known remedies based on plant extracts, homeopathic remedies, remedies based on essential oils and complex remedies based on them (chewing gum plasters, cigarettes, tablets, sweets, etc.) - "Corrida" (RU 2134585), "Antinik" (No. 2066196), Koldunok (RU 2125883), Antinikotin (RU 2157704). Products based on vitamins, sulfur and amino acids are used (US 7094787, US 2008103111).
These funds are designed to reduce cravings for nicotine, have a sedative effect, and alleviate some withdrawal symptoms. However, they have insufficient effectiveness in the withdrawal syndrome and somatovegetative consequences of quitting smoking.
The proposed drug containing nicotinic acid, Vinibis, pyrroxan and nootropil (RU 2132203). Pyroxan - eliminates the craving for nicotine. Nootropil and nicotinic acid restore and strengthen the walls of blood vessels, improve brain nutrition. The main disadvantage of this solution is its low efficacy for physical withdrawal symptoms.
In order to create a new effective anti-nicotine agent, we have proposed a composition that has a complex effect in smoking cessation.
The proposed remedy, along with the reduction of withdrawal symptoms, has a regulating and normalizing effect on the emotional sphere of a person. Reduces the urge to smoke, restores a person's "feeling of happiness", prevents depression, eliminates psychological discomfort, increases the efficiency of a person who quit smoking, and thereby greatly increases the likelihood of achieving a positive result. In addition, it has a direct anti-stress effect, because smoking cessation is a long-term stress for the body, which without correction can lead to illness and even death.
The composition includes nicotine or its substitute (nicotine-like alkaloid, antagonist of nicotinic receptors), as well as the amino acids theanine and tryptophan.
The term "nicotine" according to the present invention means the alkaloid nicotine and its derivatives (base, salts, etc.), for example, nicotine hydrochloride, nicotine sulfate, nicotine salicylate, nicotine ditartrate dihydrate and others. The term "nicotine-like alkaloids" encompasses nicotine-type compounds, preferably, but not exclusively, cytisine, lobelia hydrochloride, cotinine, myosmin, anabazine, anatabine, nornicotine, beta-nicotirine, beta-nornicothirine and nicotine N-oxides, and others. Nicotinic receptor antagonists can be represented by varenicline or its analogs.
The term "theanine" (L-theanine, l-theanine, l-Theanine, l-teanin) according to the present invention is an amino acid derived from glutamic acid (γ-glutamyl ethylamide), obtained mainly from tea leaves, as well as synthetically and microbiologically ... Any form of the amino acid L-theanine, D-theanine and DL-theanine can be used, but the L-form is preferred. The theanine of the present invention can be used either as an amino acid or as a green tea extract.
The tryptophan of the present invention can be l-tryptophan, 5-hydroxytryptophan and other biologically active forms of tryptophan and its derivatives obtained by various methods.
Nicotine and nicotine substitutes in the composition help to reduce the severity of physiological withdrawal symptoms. Theanine increases dopamine levels, has a calming and relaxing effect, but also stimulates mental activity. In addition, the amino acid theanine has the ability to reduce smoking cravings (US Pat. No. 7,094,787). L-tryptophan enhances the production of the neurotransmitter serotonin and melatonin, which are responsible for mood and sleep quality. In addition, tryptophan stimulates the release of endorphin, the level of which is sharply reduced after smoking cessation (US 2008103111).
When combined, theanine and tryptophan act synergistically. As a result, a quick correction of mental disorders in nicotine withdrawal syndrome is achieved, mood improves, a feeling of happiness appears, anxiety and fear decrease, and the desire to smoke decreases.
Thanks to the complex action of the components of the proposed tool, it became possible to reduce the dosage of nicotine substitutes, thereby reducing the risk of their side effects. Nicotine and nicotine-like alkaloids can be contained in the proposed anti-nicotine agent both in conventional dosages (for example, recommended in commercial products), and in smaller amounts. For example, nicotine from 2 mg to 1 mg, lobeline hydrochloride from 2 mg to 1 mg, anabazine hydrochloride 3 mg - 1 mg, cytisine from 1.5 mg to 0.5 mg in 1 dose.
Theanine concentration can range from 50 to 200 mg per dose, but 100-150 mg is preferred; tryptophan - 8 to 50 mg in 1 dose, preferably 20 to 40 mg.
The frequency of application of the proposed agent is selected individually, depending on the number of cigarettes smoked per day and smoking experience, the type and state of the nervous system, etc. and can vary from 4 to 6 times a day, with a gradual decrease in the frequency of intake.
The use of the agent can be started either after the complete cessation of smoking, or a sharp decrease in the number of cigarettes smoked.
The duration of the course is also selected individually and is at least 5 days and can be continued up to 4-6 weeks. In case of relapses (resumption of smoking), the course of treatment can be repeated.
The anti-nicotine agent according to the present invention can be applied in various forms, namely in the form of candies (chewing, caramel, lollipops, lozenges, etc.), chewing gum, tablets (chewing, sublingual, etc.), as well as in the form of drops, syrups , transdermal systems, compositions with controlled release, which is illustrated by the examples below.
Example 1. Chewable tablets
nicotine ditartrate dihydrate - 3.7 mg
theanine - 150 mg
tryptophan - 24 mg.
Excipients: mannitol, microcrystalline cellulose, povidone, methylcellulose, magnesium stearate, flavor, aspartame. The active ingredients are introduced into the tablet mass at the granulation stage.
Example 2. Tablets for oral administration
cytisine - 1.5 mg
theanine - 150 mg
tryptophan - 24 mg.
Excipients: lactose, starch, microcrystalline cellulose, talc, calcium stearate.
Example 3. Chewing gum
nicotine 1 mg
theanine - 50 mg
tryptophan - 8 mg.
Excipients: sorbitol, anhydrous sodium carbonate, sodium bicarbonate, flavor, glycerol, semisint.
Nicotine, theanine and tryptophan are directly mixed into the gum mass with stirring at a temperature not exceeding 50 ° C.
Example 4. Gummy candy
cytisine - 0.7 mg
theanine - 50 mg
tryptophan - 8 mg.
Candy mass - sugar, molasses, palm oil, gelatin, gum arabic, modified starch, lecithin, emulsifiers, citric acid, flavor, color.
The active composition is introduced in the form of a powder at the stage of preparation and processing of the mass of chewing candy at a temperature from 50 ° C to 35-40 ° C.
Another aspect of the invention is a special kind of anti-smoking agent for obese people. A common side effect of smoking cessation is significant weight gain. Smoking speeds up metabolism and suppresses hunger. Nicotine stimulates the release of glycogen and an increase in sugar, resulting in decreased appetite. In order to prevent a sharp increase in body weight, the composition of the anti-nicotine agent according to the present invention includes a substance that improves fat metabolism - carnitine (L-carnitine, L-camitine, Vitamin B11, vitamin Bt, levocarnitine).
Carnitine increases the oxidation of fats in the body, reduces the content of subcutaneous fat and cholesterol in the blood, and accelerates the growth of muscle tissue. The carnitine according to this invention can be used in any form: carnitine hydrochloride, carnitine tartrate, carnitine HCL, L-carnitine base, etc.
Carnitine can be incorporated into the anti-nicotine agent of the present invention in conventional therapeutic dosages known to those skilled in the art. Preferably, the average dosage in 1 dose of the anti-nicotine agent is 0.2-0.4 mg.
1. Antinicotine agent containing theanine 50-200 mg and tryptophan 8-50 mg in 1 dose.
2. An anti-nicotine agent according to claim 1, characterized in that it may additionally contain nicotine in an amount of 1-1.5 mg.
3. An anti-nicotine agent according to claim 1, characterized in that it may additionally contain an alkaloid with a nicotine-like effect, selected from the group: lobelia hydrochloride 1-1.5 mg, anabazine hydrochloride 1-2 mg, cytisine 0.5-1 mg.
Similar patents:
The invention relates to medicine, namely to psychiatry, and narcology and for the treatment of addiction. For this, complex treatment is carried out, including the introduction of homeopathic medicines, reflexotherapy effects on biologically active points (BAP) and transcranial electrical stimulation of the endorphin system.
The invention relates to medicine. Specific types of nicotine-containing chewing gums have been described that provide a high rate of buccal absorption, high plasma concentrations, especially within the first 10 minutes after application, in an individual wishing to quit smoking.
Methods are proposed for the treatment or prevention of dependence and relapse of drug use: alcohol, nicotine, marijuana, marijuana derivative, opioid receptor agonist, benzodiazepine, barbiturate and psychostimulant by administering the peroxisome proliferation activator gamma receptor agonist (PPARγ) thiazolidinedione, alone or in combination with the other agent - opioid receptor agonist, mixed partial agonist / antagonist of opioid receptors, antidepressant, antiepileptic, antiemetic, antagonist of corticotropin-releasing factor receptor 1 (CRF-1), selective antagonist of serotonin receptor 3/5-HT2 antagonist 2C or cannabinoid receptor 1 (CB1) antagonist (variants), corresponding pharmaceutical compositions with the above combinations (variants), unit dosage form (variants) and kits (variants).
Indications for use
What properties does Antinicotine phyto-collection have, how is its formula useful, how does it affect the body:
Eliminates nicotine addiction;
- Instills aversion to smoking;
- Neutralizes the craving for pleasure from smoking cigarettes;
- Gradually eliminates the attraction to the smoking pipe and chewing tobacco;
- Balances the nervous system;
- Removes toxins and toxins;
- Helps to cough up phlegm, including old ones;
- Reduces the risk of broncho-pulmonary diseases (pleurisy, bronchitis);
- Increases immunity;
- Strengthens the body.
Traditional medicine has been familiar with the fight against smoking for many centuries. Human dependence on tobacco is a real problem for many families. Therefore, the medicinal properties of plants should be considered with close attention. It is no coincidence that the reviews of our customers boil down to one thing: there is practically no colossal benefit and harm - this is what the medicinal herb is valuable for (as opposed to chemical medicines).
A wonderful folk remedy has appeared in our catalog - the collection of herbs "Antinikotin". Its composition is unique, developed specifically for the Russian Roots online store. There are no analogues of this herbal tea on the market, so it is very problematic to buy it in Moscow. But it can be ordered by mail from us. Favorable price and well-organized delivery will delight you.
Having carefully studied the products (how much it costs and how to use herbal tea), purchasing it and starting to use it, you can personally make sure that it treats it very delicately. But at the same time, the effect is persistent - after passing 1-2 courses of herbal medicine, the smoker will forever get rid of the destructive addiction.
The unique collection includes:
Ledum, licorice. Effective expectorant, enveloping agents. Helps to quickly remove phlegm, thereby relieving the body from the source of germs.
Nettle, St. John's wort. They improve the composition of the blood, purify it (thereby weakening the dependence on nicotine). Suppress the growth of bacteria, repel viral attacks. Beneficial effect on the nervous system.
Echinacea, marsh calamus. Powerful natural immunomodulators. Strengthens a weakened body, prevents the development of diseases of the respiratory system.
Horsetail, knotweed, bearberry herb. They have a diuretic effect. They help cleanse the body of toxins and toxins, break down salt formations.
Icelandic moss. Fight against tissue dystrophy. General restoration of strength, increased tone, strengthening of the body's defense mechanisms.
White mistletoe, leuzea. Prevention of hypertension by cleaning the walls of blood vessels from cholesterol plaques and clots. Relief from headaches, normalization of blood pressure.
Fireweed (ivan tea). Antiallergen. Choleretic, cleansing action. Normalization of metabolism. Improving blood circulation.
In our online store "Russian Roots" you can buy Antinicotine No. 82 herbal collection and consult on its use. Our managers will be happy to answer all your questions regarding our products, they will tell you where to buy, How much does it cost. A large assortment and excellent prices will pleasantly surprise you.
Various medicinal herbal preparations can be bought at a pharmacy in Moscow or in our online store, as well as ordered by mail. About what is usefulAntinicotine No. 82 herbal collectionWhat cures, how it is taken, you will find out by referring to the page of our site.
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Composition:St. John's wort, wild rosemary, Icelandic moss, horsetail, knotweed, leuzea, calamus, white mistletoe, nettle, licorice, echinacea, ivan tea (fireweed), bearberry, black walnut leaves.
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Method of preparation and use Antinicotine No. 82 herbal collection:
Brew dry herbal tea with boiling water at the rate of 500 ml of boiling water for 2 tbsp. l. collection. You don't need to boil - instead simmer the mixture for about 10 minutes. Then remove from the stove, leave for 1 hour. Should be taken in 1/3 cup 20 minutes after meals. Preferably 3-4 times a day.
The course is 14-15 days, then a break for 1 week and repeat. If necessary, repeat the cycle until the tobacco addiction finally leaves the smoker.
50 gr. collection is enough for 5-7 days of admission.
Reviews for herbal collection Antinikotin No. 82 indicate that the results of such treatment give remarkable results. You need to tune in to the treatment until the result is obtained and try not to interrupt the procedure. If you do not know where to buy herbal collection Antinicotine No. 82 in your region, please contact our Russian Roots online store.
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Contraindications for applicationAntinicotine No. 82 herbal collection:
Do not use in the presence of acute diseases associated with renal failure, the formation of stones in the liver, kidneys, biliary tract. Contraindicated in case of individual intolerance to individual plants, during pregnancy and breastfeeding. Not recommended for children under 12 years of age.
Buy a unique collection of herbs Antinicotine No. 82 can be found on the pages of the online resource "Russian Roots". The consumer can order the product by mail or courier.The affordable price of herbal preparations and customer reviews will help you make a balanced choice in favor of one or another drug.
If you cannot buy in Moscow due to remote residence from the capital, place an order on our website. This is easy enough to do. Specify how much the product costs and what are the delivery conditions, how to pay.
Buy Antinicotine No. 82 herbal collection
you can in our online store "Russian roots",
Smoking is a drug addiction, but socially encouraged. A huge number of anti-smoking campaigns are held annually in the world, but the number of smokers is not decreasing. The proceeds from the sale of legal drugs are steadily replenishing the state budget. And meanwhile, almost every smoker has tried to quit smoking at least once. Mark Twain has “thrown” a thousand times and has done it “easily” each time.
There are an unimaginable number of ways and technologies to resist smoking - willpower, pharmaceuticals, mysterious oriental techniques (acupuncture, acupuncture). And every remedy can become the final solution to the problem, and may enter the rank of "another unsuccessful attempt".
Pharmacological drugs for smoking cessation
What drugs help to quit smoking?
Pharmacies and online storefronts offer a variety of anti-smoking products. Tablets, sprays, electronic cigarettes - it's easy to get confused, but how to choose the best remedy? Unfortunately, the reviews for each drug are conflicting. Fortunately, each of the drugs can be a salvation for the nicotine drowning in the sea.
Anti-smoking pills occupy a special place in the drug market. Conventionally, in this group of medicines, three types can be distinguished - nicotine substitutes (,), antidepressants and tranquilizers (,) and tablets of a "repulsive" nature (,). Some drugs combine two or more effects.
Smoking - one of the hardest addictions in the world... Experienced hypnologists claim that it is easier to program the subconscious mind to give up alcohol rather than nicotine. Therefore, it is inappropriate to talk about the exceptional effectiveness of tablets. But they may well contribute to abandonment and mitigate withdrawal symptoms when there is a strong belief in quitting.
When you quit smoking, you need to help your lungs clear. Read,. List of useful methods and folk remedies.
Are e-cigarettes harmful or useful? Read everything about the device and the principles of exposure, reviews of doctors and opinions of smokers.
"Tabex" from SOFARMA PLC
The active component of Tabex tablets from the Bulgarian manufacturer is cytisine, belonging to the class of alkaloids. Cytisine is extracted from the creeping broom plant. The substance resembles nicotine in nature and acts on nicotinic receptors - this is how the nicotine replacement effect is caused. A person's craving for a cigarette decreases due to the satisfaction of a physical need.
When trying to smoke the body feels overdose- nausea, dizziness and other unpleasant symptoms. A person is forced to reduce the number of cigarettes smoked, and ultimately - to give up them. Tabex acts in two ways - it turns a person away from a cigarette and reduces the severity of withdrawal symptoms. The body continues to receive a portion of the nicotine analogue, which means it does not suffer from hunger.
The scheme of using Tabex is quite specific - six times a day for 1-3 days, 4-25 days - the portion is gradually reduced from five tablets to one. The exact scheme of use is indicated in the instructions. If by the fifth day a person could not stop smoking, taking the pills is stopped due to the development of nicotine intoxication. The course can be resumed in at least 2-3 months.
The drug has a lot of contraindications, side effects. An overdose of Tabex poses a threat to life - with any suspicion, calling an ambulance is mandatory.
Reviews
Tabex tablets are the most popular smoking cessation tool due to the affordable price and good advertising campaign at the launch of the product. Reviews of the drug as a whole positive.
- “Smoking experience - 9 years. I tried everything - from lollipops to expensive plasters. Tabex saw clearly according to the instructions - this is important. On the third day, there was an aversion to smoke. My strong urge to quit may have helped, but Tabex was good support. There are many contraindications, as well as side effects. But in comparison with the monstrous harm of smoking - everything can be survived. "
- “It helps to quit, but does not do all the work for the smoker, you need desire. The main thing is that it eliminates physical breakdown if you do everything according to the instructions. With psychological dependence, alas, you need to work independently or with a psychotherapist. Quit smoking for two years. He started smoking again due to stress. Conclusion - the drug works like a good crutch, but will not help a sore head. "
The average price of Tabex No. 100 tablets in Russia is 410-850 rubles.
Champix from Pfizer Manufacturing Deutschland
The active component of the German Champix tablets is varenicline, which acts on the nicotinic acetylcholine receptors in the brain. The drug was created with the aim of influencing two components of nicotine addiction - satisfaction from smoking, withdrawal symptoms.
Varenicline binds to receptors and causes the release of dopamine, the hormone of pleasure, but its amount is slightly less than with ordinary smoking.
The craving for cigarettes gradually, but decreases, the withdrawal syndrome is easier. When trying to smoke Champix blocks the receptors - the person does not get pleasure from the cigarette.
Champix is taken for 3 months, which are divided into 3 stages - starting (2 weeks), main (8 weeks), final (2 weeks). Each stage has its own package with tablets - 25 tablets of 0.5 mg (I), 112 tablets of 1.0 mg (II), 28 tablets of 1.0 mg (III). The drug has been in development for 10 years and won the Galen Prize - highest pharmaceutical award... The manufacturer claims that 9 out of 10 customers who use Champix quit smoking.
Reviews
Reviews of real smokers really testify to the effectiveness of the pills. Frequent complaints are nausea and a slight deterioration in well-being, however, the manufacturer warns about these side effects in the instructions.
- “Champix was my last hope. The drug is good, I quit smoking in the third week of admission. I can recommend buying only the middle course, it should be enough. The pills are still expensive. Of the minuses - I was very nauseous in the morning and began to gain weight, but hardly the last from the pills. "
- “During the first week of taking Champix I smoked a standard pack a day. I did not feel any effect of disgust or replacement. As soon as I started to drink 1 mg each - on the very first day after the cigarette I felt very twisted - I felt nauseous, could not eat, and had a severe headache. The smell and taste of cigarettes caused an attack of vomiting. I still wanted to smoke, but the thought of the consequences discouraged all desire. So I gave it up. "
The cost of Champix tablets in Russia: 0.5 mg (28 tablets) - from 1050 rubles, 1 mg (112 tablets) - from 3200 rubles.
"Brizantin" from Materia Medica
There are two active components in the composition of Brizantin - affinity purified antibodies to the brain-specific protein S-100 (0.006 g) and to the type 1 cannabinoid receptor (0.006 g). The complex of these substances reduces the craving for psychoactive substances, eliminates the phenomena of withdrawal symptoms, reduces the ideational component (obsessive thoughts about the need to smoke). The drug correlates somatovegetative disorders that occur in smoking cessation - insomnia, palpitations and others.
Brizantin - lozenges, taken 2-3 times a day, one at a time... The number of tablets can be increased to 6 in case of an acute urge to smoke. The drug is distinguished by a small number of contraindications and side effects, mainly associated with individual intolerance to any component.
Reviews
Reviews about Brizantin are often neutral.
- “I learned about Brizantine thanks to advertising. I drank a course according to the instructions. If Tabex at least somehow declares itself, then Brizantin behaves like a lollipop - he sucked it and forgot. An increase in the dose to 6 tablets did not affect the symptoms. Money is not a pity - not expensive. Quit smoking solely for the sake of his wife. I think that the role of Brizantine is zero. "
- “Brizantin suited me - gentle, effective, inexpensive, it also suppresses appetite. I quit smoking and didn’t gain any weight ”.
The cost of Brizantin tablets in Russia is 210-350 rubles.
Nicorette by McNeil
Nicotine pills - Nicorette
Nicorette chewable tablets belong to the class of nicotine substitutes. The active ingredient of the drug is medical nicotine (nicotine ditartrate dihydrate). The tablet serves as a supplier of pure nicotine to the body, which, dissolving in saliva, is absorbed through the oral mucosa and becomes part of the bloodstream.
In case of weak dependence, the recommended dose is 8-12 tablets per day, the dose of 30 tablets should not be exceeded for any degree of dependence. The course of active use of Nicorette is on average 3 months, after which the number of tablets is gradually reduced.
With the use of Nicorette, withdrawal symptoms are easier, cravings for cigarettes are reduced, but there is no aversion to them.
Reviews
Reviews of the drug often note one of the unpleasant symptoms - sore throat. The action of the drug is called sparing, frequent breakdowns are noted after stopping the use of pills.
- “I get by with 12 pills a day, I have not smoked for a month. I tried to skip a couple of days - the lack of a "crutch" is immediately felt. In general, the drug is not bad, but I am afraid that without it I will again reach for a cigarette. "
- “Any remedy will help you quit smoking if you have a strong desire. I tried Tabex, plasters, an electronic cigarette - each of them was effective in the presence of self-control and self-hypnosis. Nicorette is a fairly budgetary means of reinforcing your intention to quit. And the body is not so hard to wean from the lack of nicotine - to some extent, it is present. "
The cost of Nicorette in Russia is from 350 rubles for 30 tablets.
Zyban by GlaxoSmithKline
Zyban tablets are in the class of antidepressants and are available with a prescription. The active ingredient of the drug is bupropion hydrochloride, which is one of the most effective and well-known antidepressants. The mechanism of action of Zyban is incredibly simple - bupropion affects the production of an additional portion of dopamine (the hormone of pleasure). A quit smoking person experiences a phase of withdrawal symptoms in a state of euphoria. Zyban is not a nicotine replacement therapy, unlike most analogues.
Taking the pills starts one week before the expected day of quitting smoking. The drug prepares the body to give up the usual pleasure, relieves anxiety, nervousness, angry outbursts. Its auxiliary components help quit smoking to not gain weight.
The recommended therapeutic course is at least 7 weeks, during the first of which the patient takes one tablet a day. Subsequent dosage (from the 8th day) - 3 tablets per day. The drug, after its appearance on the market, was soon withdrawn due to the increased incidence of epileptic seizures. The examination found that patients exceeded the recommended dose.
Tabex is a modern anti-smoking pill that has no analogues. Their main component is cytisine, a substance similar to nicotine, but less toxic. How to fight smoking cravings with Tabex? How long will the effect last?
Smoking pills Tabex
Tabex anti-nicotine tablets are produced by 2 Bulgarian companies - Sopharma AO and Pharmachim. The drug is of plant origin and is used to treat chronic smoking addiction. In Russia, the average price of a drug varies from 700 to 900 rubles per 100 tablets.
Tabex is the only anti-smoking drug of its kind that is mediated by cytisine. This substance is an alkaloid. The mechanism of action is the same as that of nicotine, but the toxicity of the drug is significantly lower.
The anti-smoking drug Tabex is intended both to completely get rid of tobacco addiction and to reduce the number of cigarettes smoked. The effectiveness of the drug in both cases was confirmed by the results of clinical trials. In addition, experts noted an improvement in the condition of nicotine addicts due to the cessation of chronic nicotine poisoning.
Composition
The active substance of Tabex is cytisine. Its content in 1 tablet is 1.5 mg. Lactose monohydrate is used as a sweetener; this substance is also a source of energy.
As part of the shell of the tablets there is a dye E172, due to which they acquire a beige color.
Operating principle
Like nicotine, cytisine has the following effects on the body:
- Excites CNS nicotinic receptors.
- Increases blood pressure.
- Promotes the release of adrenaline.
As an agonist of acetylcholinergic receptors, cytisine prevents the attachment of nicotine to them, as a result of which dependence is reduced. At the same time, a person begins to feel an unpleasant taste when smoking. This can help you to quit cigarettes and ease the onset of withdrawal symptoms.
In the video, the principle of action of Tabex tablets:
Instructions for use
When taking Tabex according to the recommended scheme, at first, you may experience the same sensations as when you smoke too many cigarettes. If it is difficult to tolerate this condition, it is allowed to reduce the daily dose of pills and adjust the regimen. It is important that only a doctor should tell you how to take Tabex pills from smoking, who will select the optimal regimen.
Initial course
The first 3 days they drink 1 tablet 6 times a day, observing two-hour intervals between doses of the drug. At the same time, it is necessary to reduce the number of cigarettes smoked.
If after 3 days the result is not observed, you need to stop taking the pills for smoking, and after a couple of months try to drink them again.
Main course
If the start of treatment was successful, then continue to take the medicine according to the following scheme:
- 1-3 days: 1 tablet every 2 hours (total 6 per day).
- 4-12 days: 1 each after 2.5 hours (5 in total).
- Day 13-16: 1 every 3 hours (4 in total).
- 17-20 days: 1 every 5 hours (3 in total).
- 21-25 days: 1 every 6-8 hours (1-2 in total).
According to this scheme, on the 5th day you should completely give up cigarettes. If, while taking Tabex smoking pills, you continue to smoke in the original volume, nicotine poisoning is possible.
Contraindications and side effects
Tabex has a number of contraindications, including:
- acute myocardial infarction;
- pulmonary edema;
- arrhythmias;
- exacerbation of peptic ulcer disease;
- bronchial asthma;
- high blood pressure;
- complicated atherosclerosis;
- bleeding from large vessels;
- violation of cerebral circulation in the recent past;
- pregnancy and lactation;
- hypersensitivity to components.
Also, before drinking the drug, you should find out about the possible side effects.
For example, the drug may not be accepted by the digestive system. In this case, constipation or diarrhea, abdominal pain, nausea, disturbances in appetite and taste of food, dry mouth are possible.
On the part of the nervous system, sleep disturbances and increased excitability are possible.
The cardiovascular system may respond to the drug with tachycardia, a slight increase in blood pressure, shortness of breath, pain in the sternum.
In addition, as a side effect, dramatic weight loss, increased sweating, myalgia and allergies are possible. However, most side effects go away on their own when you stop taking the pills. No additional treatment is required.
Photo of Tabex smoking tablets:
Overdose
With an independent increase in the dose of the drug, an overdose is possible. It can be recognized by its characteristic symptoms:
- nausea and vomiting;
- lethargy;
- tachycardia;
- respiratory paralysis;
- dilated pupils.
If such signs appear, it is necessary to urgently take the person to the hospital. There he will undergo gastric lavage, and also prescribe symptomatic drugs, including anticonvulsants, analeptics, infusion solutions, cardiotonics.
